A melatonina como suplemento alimentar, benefícios e malefícios: uma revisão integrativa

Abstract

Introduction: Melatonin supplementation is well known for its role in controlling the circadian cycle and consequently improving sleep quality, however in recent years other possible benefits of the substance have been attributed to humans. In Brazil, the prescription of Melatonin was recently released by ANVISA, being classified as a food supplement with free sale and without the need for a prescription. Objective: to understand the role of melatonin as food supplementation and what benefits and harms. This is an integrative literature review, using the following databases: PubMed/MEDLINE, EMBASE and LILACS, in the Catalog of Theses and Dissertations of CAPES and in the Brazilian Digital Library of Theses and Dissertations (BDTD) without limitations related to the language or year of publication. Intervention studies with adults and the elderly that sought to evaluate the effect of melatonin supplementation on the improvement of sleep quality were included. The synthesis of data took place through a table identifying the articles, method, main information regarding the theme under study and conclusions. Result: The final sample consisted of 12 articles. The analysis of the productions 8 showed that in 2021 there was the highest number of articles published (6=50%). Regarding the place of publication, the majority (10=83%) is international.